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Structural Biologist

Date: 19-Jan-2022

Location: Melbourne, VIC, AU

Company: CSIRO

Acknowledgement of Country

CSIRO acknowledges the Traditional Owners of the land, sea and waters, of the area that we live and work on across Australia. We acknowledge their continuing connection to their culture and pay our respects to their Elders past and present. View our vision towards reconciliation

The Opportunity


  • ​​​​​​Use your expertise in protein x-ray crystallography and structure determination
  • Contribute to the development of new medical treatments and technologies
  • Innovative and collaborative workplace with fantastic flexibility


CSIRO’s Manufacturing Business Unit brings together multi-disciplinary scientific and engineering capabilities using world-class infrastructure to partner with industry in order to develop innovative products and processes to allow Australian manufacturers to be globally competitive and environmentally sustainable. The Biomedical Manufacturing Research Program works with biomedical companies to deliver new medical treatments and technologies that benefit millions of people in Australia and overseas, helping them live longer, healthier, and more productive lives.

As a Structural Biologist, you will join the Protein Engineering Team and will apply your knowledge and experience in structural biology and associated techniques. You will design and conduct protein x-ray crystallography experiments to solve structures and perform biophysics experiments to explore protein structure-function relationships. Working as part of a multidisciplinary team, you will contribute towards the development of new medical treatments and technologies.

Your duties will include:

  • Under limited direction, assisting in the planning and preparation of research proposals and carry out research investigations, requiring originality, creativity and innovation. 
  • Designing and conducting protein crystallography experiments including x-ray data collection, and protein structure solution, analysis, and interpretation.
  • Applying biophysical research techniques to explore protein structure-function relationships.
  • Collaborating with protein and medicinal chemists in progressing hit compounds from high throughput screening campaigns.
  • Presenting results in a meaningful format, prepare reports for clients and/or write scientific papers for publication.  


Location: Melbourne (Clayton) VIC

Salary: AU$102k - AU$111k plus up to 15.4% superannuation

Tenure: Indefinite

Reference: 80284

To be considered you will need:

  • A PhD (or an equivalent combination of qualifications and research experience) in a relevant field such as Structural Biology or Biophysics/Biochemistry. 
  • Demonstrated experience in protein x-ray crystallography and structure determination and analysis with a focus on ligand-bound protein structures.
  • Expertise in biophysical analysis of proteins and experience in the interpretation of a variety of biochemical and biophysical data. 
  • Experience in the management of crystallographic data.
  • Excellent communication skills and a sound history/record of publication in peer reviewed journals and/or authorship of scientific papers, reports, grant applications or inventorship on patents applications.
  • A history of undertaking original, creative and innovative research by generating and pursuing novel ideas and solutions to scientific research problems.
  • To be able to work effectively as part of a multi-disciplinary project team, plus the motivation and discipline to carry out autonomous research.


For full details about this role please review the Position Description


Applications for this position are open to Australian Citizens, New Zealand Citizens and Australian Permanent Residents.

Appointment to this role is subject to provision of a national police check and may be subject to other security/medical/character requirements.

Flexible Working Arrangements

We work flexibly at CSIRO, offering a range of options for how, when and where you work. 

Diversity and Inclusion

We are working hard to recruit people representing the diversity across our society, and ensure that all our people feel supported to do their best work and feel empowered to let their ideas flourish. 


At CSIRO Australia's national science agency, we solve the greatest challenges through innovative science and technology. We put the safety and wellbeing of our people above all else and earn trust everywhere because we only deal in facts. We collaborate widely and generously and deliver solutions with real impact. 

Join us and start creating tomorrow today!

How to Apply

Please apply on-line and provide a cover letter and CV that best demonstrate your motivation and ability to meet the requirements of this role.

Applications Close

6 February 2022, 11:00 pm AEDT